A Comprehensive Review on Therapeutic Potential of Herbal Plants in Diabetes and Diabetes Associated Problems

Diabetes prevalence has increased dramatically in almost every part of the world in recent decades. The increased number of persons with diabetes or those who have had diabetes for a longer period is anticipated to change the disease profile in many communities throughout the world, owing to a higher frequency of diabetes-specific comorbidities such as kidney failure and peripheral artery disease. The epidemiology of other illnesses commonly linked with diabetes, such as infections and cardiovascular disease, may also shift, with significant consequences for the quality of life, healthcare needs, and economic expenditures. Diabetes (DM) is becoming more common at an alarming pace throughout the world. According to the International Diabetes Federation, an estimated 415 million individuals worldwide suffered from this illness in 2015. Diabetes complications include increased morbidity, disability, and death, posing a danger to the economies of all countries, particularly emerging ones. The current understanding of the global burden and variance in diabetes-related complications is inadequate. According to the available statistics, rates of myocardial infarction, stroke, and amputation are falling among diabetics, coinciding with lower mortality. However, the majority of these statistics originate from research conducted in only a few high-income nations. Other diabetic consequences, such as end-stage renal disease, retinopathy, and cancer, have received less attention. Obesity, insulin resistance, hyperglycemia, and hyperlipidemia are all variables that influence the development and progression of diabetes problems. In this review, we have included all the major complications and their pathophysiology along with their possible mechanism of action and the possible treatment with herbal or medicinal plants. This review will explore new ways of the diabetic complications around the globe.